The science behind Dryello
The Science Behind Dryello
Medically reviewed by Dr. Carl Schanbacher
Medically reviewed by Dr. Carl Schanbacher — board-certified by the American Board of Dermatology and a member of the American College of Mohs Surgery.
Last reviewed: August 2026
Dryello contains tolnaftate 1%, an antifungal active ingredient for over-the-counter use, in a dry stick that glides on smoothly. Its efficacy and safety were evaluated in a dedicated clinical trial program, and our NEW fragrance-free formula was tested in an independent, dermatologist-supervised skin safety study. Here’s what the data shows.
87% Cure Rate
Across two clinical cohorts (n=39 at 4 weeks, per-protocol analysis), 87% of participants were mycologically cured of athlete's foot after 4 weeks of twice-daily use.1 Itching was reduced by 40% in as early as 2 weeks.1 Participants also rated the product highly for comfort and ease of use throughout treatment.
Shop the Athlete's Foot Treatment StickSafety
No serious adverse events occurred in either clinical study. Two mild, unrelated adverse events were reported and fully resolved.1
Non-Irritating & Non-Sensitizing
In an independent repeat insult patch test (HRIPT) of 104 people, Dryello's fragrance-free formula was non-irritating and non-sensitizing, with no reactions observed. The study was supervised by a board-certified dermatologist.3
Explore the fragrance-free formula